Urinary β-trace protein

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Urinary β-trace protein

The screening for chronic kidney disease (CKD) patients needs the measurement of serum markers like creatinine. Our previous results indicated that urinary excretion of β-trace protein (BTP), a low-molecular-weight protein (23-29 kDa), is increased in CKD patients from stage 2. The aim of this study was to assess the major determinants of urinary excretion of BTP and to evaluate its feasibility...

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Serum and urinary markers of early impairment of GFR in chronic kidney disease patients: diagnostic accuracy of urinary β-trace protein.

The screening for chronic kidney diseases (CKD) patients with impaired GFR needs the measurement of serum creatinine (SCr) or cystatin C (SCys). GFR can also be predicted from SCr or SCys with different formulas. The aim of this study, performed in a group of CKD patients with different levels of GFR, was to evaluate the possibility to select the patients with a GFR <90 ml·min(-1)·1.73 m(-2) by...

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β-trace protein (prostaglandin D synthase) - a stable and reliable protein in perilymph

OBJECTIVE Beta-trace protein (beta-TP) has been analysed in human cerebrospinal fluid (CSF) and other body fluids. Beta-trace protein is a very sensitive and specific clinical marker and can confirm reliably the presence of CSF in patients with a suspected CSF leakage. DESIGN Perilymph specimens from the scala vestibuli (n=10) and from the lateral semicircular canal (n=4) were taken from pati...

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Beta trace protein as GFR marker in children

Background and Objective: Serum creatinine is the most used endogenous marker of glomerular filtration rate (GFR), but it also has multiple limitations. Therefore, some surrogate GFR markers, such as beta trace protein, have been introduced for GFR estimation. The aim of our study was to estimate GFR by serum beta trace protein using three available equations and compare them to DTPA GFR as the...

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Urinary beta-trace protein gene expression analysis in type 2 diabetes mellitus patients

OBJECTIVE To evaluate the gene expression of beta-trace protein in urine of diabetic patients, with no reduction in glomerular filtration rate, which was defined as below 60mL/min/1.73m2. METHODS Type 2 diabetes mellitus patients were recruited, and a group of non-diabetic individuals served as control. Beta-trace protein gene expression was analyzed by quantitative PCR. Blood samples were co...

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ژورنال

عنوان ژورنال: Medicine

سال: 2016

ISSN: 0025-7974

DOI: 10.1097/md.0000000000005553